Clinical, Histological and Direct Immunofluorescence Study in Immunobullous Diseases
نویسندگان
چکیده
منابع مشابه
A cross-sectional study of clinical, histopathological and direct immmunofluorescence diagnosis in autoimmune bullous diseases
Background: Immunobullous diseases are morphologically heterogeneous and the differentiation between various subtypes is essential for proper treatment and prognosis. The aim of our study was to analyze and correlate clinical, histopathological, and immunofluorescence findings in autoimmune bullous diseases.Method: A c...
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OBJECTIVE Autoimmune bullous diseases are heterogeneous diseases and the differentiation between the various bullous disease is important for treatment and prognosis. Direct immunofluorescence microscopy is still the gold standard in differentiating these diseases. Our aim was to determine the diagnostic accordance between clinical and histopathological/direct immunofluorescence diagnosis of pa...
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Background & Objective: Autoimmune bullous diseases are associated with autoimmunity against structural components in the skin and mucous membranes. Autoantibodies are against the intercellular junctions in pemphigus disease and hemidesmosomal unchoring complex in pemphigiod diseases and epidermolysis bullosa aquisita. The tissue-bound and circulating serum autoantibodies can be detect...
متن کاملImmunofluorescence in Oral Pathology—Part III: Pathology and Immunofluorescent Patterns in Intraepithelial Immunobullous Disorders
Dermatologic disorders frequently parallel with oral involvement which dental practitioners should be familiar with. In continuation with part II, the immunofluorescence patterns in the intraepidermal pemphigus group and its variants: Pemphigus vulgaris (PV) and paraneoplastic pemphigus (PNP) are dealt in this section. Also, a brief note is added on other mucocutaneous disorders showing similar...
متن کاملSensitivity of direct immunofluorescence in oral diseases. Study of 125 cases.
UNLABELLED Direct immunofluorescence (DIF) is widely used for the diagnosis of bullous diseases and other autoimmune pathologies such as oral lichen planus. There is no evidence in the literature on how the following variants influence the detection rate of DIF: intraoral site chosen for the biopsy, perilesional locus or distant site from the clinical lesion, number of biopsies and instrument u...
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ژورنال
عنوان ژورنال: IOSR Journal of Dental and Medical Sciences
سال: 2016
ISSN: 2279-0861,2279-0853
DOI: 10.9790/0853-150765961